Endocrine Abstracts

Background and aim: The clinical significance of papillary thyroid microcarcinoma (PTMC) is debatable. The purpose of this study is to analyse the clinicopathological characteristics of patients with PTMC and document the risk factors for poor prognosis.Materials and methods: Eighty-eight patients (18 males, 70 females) were included in the study. Clinical and laboratory parameters were recorded.Results: The mean age of the patient...

Objective: Patients with differentiated thyroid carcinoma have an increased prevalence of insulin resistance and, diabetes increases the risk of thyroid cancer. In this study we aimed to evaluate tumor features in diabetic and non-diabetic differentiated thyroid cancer patients.Methods: One hundred patients with differentiated thyroid cancer were enrolled in the study. Twenty one of the 100 patients were diagnosed as diabetic and 79 non-diabetic. All par...

Introduction: Here, we present a case of epithelial breast cancer releasing iPTH thereby causing MAH.Case report: A 48-year-old woman with metastatic breast cancer was consulted for hypercalcemia. Previous medical record was insignificant except for nephrolitiasis. She had a left mastectomy+left axillary lymph node dissection in another hospital. Prior to surgery no calcium levels were obtained. Pathology revealed infiltrative ductal carcinoma. Postopera...

Acromegaly is a rare and serious syndrome and commonly associated with pituitary neoplasm. Classic cause of acromegaly in adults is the tumors of the somatotrophs that secrete growth hormone. Cirrhosis is the end stage of chronic liver disease and commonly cause of death. It is characterized by diffuse hepatic fibrosis resulting in altered construction of the lobular parenchyma with widespread connective tissue septae, circumscribed regenerative nodules of hepatocytes and anas...

Background and aim: Serum Cystatin C has been shown to be associated with the progression to prediabetes and type 2 diabetes mellitus. High cystatin levels were also found to be associated with body mass index. The aim of this study was to evaluate cystatin C levels in diabetic and prediabetic patients ant its association with anthropometric measurements and insulin resistance.Methods: Twenty four patients with diabetes, 17 patients with prediabetes and ...

Adiponectin, is an adipocyte derived hormone possess insulin-sensitizing, antiatherogenic, and antiinflammatory properties. The aim of this study to evaluate adiponectin levels at acromegalic patients according to healthy subjects in relation with ecocardiographic findings. We included 30 subjects (15 male, 15 female) were diagnosed as acromegaly and 30 healthy (10 male, 20 female) subjects. Mean ages of both group were similar. Serum glucose, insulin, GH, IGF1 (insulin like g...

Background and aim: Hashimoto’s Thyroiditis pathogenesis remains unclear in spite of many factors currently suggested. Aim of the study was to explore the relationship between hepatocyte growth factor (HGF) and Hashimoto’s Thyroiditis (HT), goiter formation, and to see if HGF levels are adjusted by TSH suppression.Materials and methods: Sixty-one premenopausal women who admitted our department between November 2010-September 2011 were enrolled ...